PGS and NGS Genetic Screening
Sunshine provides efficient genetic screening in the form of PGS (Preimplantation Genetic Screening) and NGS (Next-Generation Sequencing) programs. These tests help clients to make sure their family complement will be successful and without any possible genetic pathologies. Generally speaking, proper NGS analysis and PGS testing provided by qualified specialists will undermine all risks when you are going to have a baby with the help of reproductive medicine, in particular, with in vitro fertilization and will increase the pregnancy success rate.
Quality PGS & NGS Analysis with Sunshine Genetic Screening Tests
Well, the thing is that if any errors occur during germ cells formation or merging, the born individual may have serious deviations or problems during the one’s further reproduction. Fortunately, contemporary medical technologies can help to prevent all these issues and so to minimize risks of disabled children birth. Genetic screening in a form of NGS analysis and PGS comes as a number-one method for detecting possible abnormalities at the genetic level. Sunshine fertility experts will gladly provide you with high-quality assistance and support during the whole testing process.
Preimplantation Genetic Screening (PGS)
Basically, the PGS is a medical procedure used to assess the state of an embryo’s chromosomes. The results of this test help doctors decide whether the embryo is suitable for conception. Based on PGS results, the healthiest and potentially most productive embryo can be selected based on an analysis of chromosomal deficiencies. The most prominent deficiency detected by preimplantation genetic screening is called aneuploidy.
PGS Is Best for Aneuploidy Detection
Aneuploidy describes embryos which have one too little or one too many chromosomes. Aneuploid embryos also can be selected for the transfer to the uterus because they look the same as the ones without any pathology. After the transfer of this kind of embryos, there still might be no pregnancy or a miscarriage may occur on an early stage. Moreover, aneuploidy may cause the birth of a child with disease marked by mental or physical retardation. With the PGS testing results, specialists can detect aneuploidy and prevent the transfer of the aneuploid embryo to the uterus and so to minimize the risk of birth of a child with deviations.
Reasons to Apply for Preimplantation Genetic Screening
If you want to make sure the embryo has no genetic abnormalities, you definitely have to go through the test to get PGS results. However, there are some vital reasons to apply for this method, and they include:
- woman’s age is over 37 years old;
- emale partner is over 35 years old and, having embryos with good morphology, the one can not become pregnant for a long time;
- unexpected and unexplained infertility of young couples;
- two or more spontaneous abortions and two or more unsuccessful IVF cycles;
- poor quality of your partner’s sperm or men’s infertility;
- one or both parents have mutations on the genetic level;
Next-Generation Sequencing (NGS)
When it comes to the genetic screening, it is crucial to pick a method that perfectly fits your situation. Sunshine offers a full NGS analysis which is the most innovative method of preimplantation genetic diagnosis. Thanks to its effectiveness and high accuracy, next-generation sequencing allows medical staff to avoid misleading results and has recently been replacing other possible methods worldwide. Additionally, NGS program is safe for the embryo as it allows to handle the biopsy starting from the fifth day of embryo development when the one already contains a required number of cells.
NGS Is Best for Mosaicism Detection
Being the advanced and the most up-to-date method of genetic screening, NGS is based on the determination of DNA sequencing. This is what makes NGS analysis stand out among other techniques. Well, NGS is a sensitive way of screening that allows experts to detect such an essential thing as mosaicism. Basically, mosaicism means the presence of cells with diverse sets of chromosomes. If the particular embryo has this issue, it may cause a pregnancy miscarriage or the birth of a child with a dangerous pathology that may affect the one’s life. NGS helps to detect the mosaicism on the pre-implantation stage. Moreover, it allows specialists to choose only genetically-healthy embryos for a further transfer and increases the level of successful gestation in general.
We at Sunshine serve you with the latest methods and solutions and try to do our best to help you enjoy the birth of a healthy baby.
Reasons To Apply For Next-Generation Sequencing
NGS analysis is helpful if you want to prevent any possible issues with the health of your future baby. We highly recommend you to apply for this genetic screening method in case:
- you have multiple unsuccessful attempts to have a baby through the in vitro fertilization;
- you are going to become a parent in a mature age;
- you had a miscarriage after the ninth week of pregnancy;
- your spouse, you or anybody of your closest family members suffers from a serious hereditary disease.
Sunshine egg donation agency aims at providing the best services for our intended parents, so we are always keeping up with the most recent advances in medical science and technology.
If there is still something unknown for you concerning the most effective genetic screening methods that Sunshine provides, please, take a look at the section of frequently asked questions.
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